Validation of New Type Radiopaque Marker in the Evaluation of Colonic Transit Time
Brief Summary
The goal of this clinical trial is to learn if the local made colonic transit capsule can be use to diagnose slow transit constipation. The main questions it aims to answer are: * Does the local made colonic transit capsule correlate with the standard colonic capsule in the diagnosis of slow transit constipation? * Does the number of remained radiopaque marker similar between the two test after five days of ingestion? Researchers will compare the local made colonic capsule with the standard Sitzmark colonic capsule to see the correlation. Participants will: * Take both local made colonic capsule and Sitzmark colonic capsule at the same time. * Obtain abdominal x-ray 5 days after capsule ingestion. * Keep a diary of their symptoms and medication used during investigation.
Eligibility
Age Range
Gender
Healthy Volunteers
Detailed Criteria
Inclusion Criteria: * Healthy volunteers with normal bowel habit not meet the criteria for functional constipation and irritable bowel syndrome with constipation according to Rome IV criteria * Participants with constipation according to Rome IV criteria Exclusion Criteria: * Previous abdominal surgery * Participants at risk for intestinal obstruction such as endometriosis, history of intra-abdominal infection * Receive medication which affect colonic transit such as opioids * Pregnancy
Conditions
Interventions
Siriraj gastrointestinal transit capsule
The Siriraj gastrointestinal transit capsule is a local made colonic transit capsule. Each capsule contains 6 circular-shaped radiopaque markers.
DEVICESitz-Markers
The standard Sitzmark colonic capsule containing 24 ring-shaped radiopaque markers.
DEVICETrial Locations
No locations are currently recruiting participants.
Faculty of Medicine Siriraj Hospital, Mahidol University
Bangkoknoi, Bangkok, Thailand
Sponsor Information
Lead Sponsor
Mahidol University
Type: OTHER