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Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients

Recruiting
7 recruiting sites
Start: Jun 28, 2024
NCTNCT06537557

This trial is currently recruiting participants

7 locations available for registration

Brief Summary

Heat stroke is a life-threatening clinical syndrome characterized by an imbalance between heat production and heat dissipation in the body, resulting from exposure to hot and humid environments and/or strenuous exercise. It is defined by an elevated core temperature exceeding 40°C and central nervous system abnormalities, accompanied by multi-organ dysfunction. The severity of cellular and tissue damage in heat stroke patients depends on the peak temperature reached and the duration of hyperthermia. Rapid reduction of core temperature can halt cellular damage, quickly reverse organ dysfunction, and improve patient outcomes. Therefore, early identification and rapid cooling are crucial to prevent irreversible damage and death in heat stroke patients. However, there is a lack of systematic and specific protocols to guide emergency medical staff in the standardized and effective management of body temperature in heat stroke patients. To address this, our research team previously developed an early in-hospital temperature management protocol for heat stroke patients based on the best available evidence, expert consultations, and expert panel meetings. This study aims to validate the feasibility and effectiveness of the protocol through clinical research, providing a basis for clinical practice.

Eligibility

Age Range

18 Years - N/A

Gender

All

Healthy Volunteers

Not Accepted

Detailed Criteria

Inclusion Criteria: * Patients admitted to the emergency department and diagnosed with heat stroke according to the China expert consensus on Heat Stroke Exclusion Criteria: * transferred from another hospital and body temperature \< 39.5℃; discharged within 4 hours, and subsequent body temperature or outcomes were unavailable; required immediate cardiopulmonary resuscitation; had other serious diseases, such as massive cerebral haemorrhage or severe trauma.

Conditions

Heat Stroke

Interventions

the early in-hospital temperature management protocol for heat stroke patients

The early in-hospital temperature management protocol for heat stroke includes early identification, selection of cooling methods for rapid cooling, precise target temperature management, and dynamic monitoring. Effective temperature management will be implemented for heat stroke patients to improve their outcomes.

OTHER

Trial Locations

7 locations currently accepting registrations. Choose a recruiting location below to register your interest.

Yongkang First People&#39;s Hospital

Yongkang, Zhejiang, China

Recruiting

Dongyang People's Hospital

Dongyang, China

Recruiting

The Second Affiliated Hospital of Zhejiang University School of Medicine

Hanzhou, China

Recruiting

Jinhua Municipal Central Hospital

Jinhua, China

Recruiting

Jinhua People's Hospital

Jinhua, China

Recruiting

Lanxi People's Hospital

Lanxi, China

Recruiting

Yiwu Central Hospital

Yiwu, China

Recruiting

Sponsor Information

Lead Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Type: OTHER