Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients
This trial is currently recruiting participants
7 locations available for registration
Brief Summary
Heat stroke is a life-threatening clinical syndrome characterized by an imbalance between heat production and heat dissipation in the body, resulting from exposure to hot and humid environments and/or strenuous exercise. It is defined by an elevated core temperature exceeding 40°C and central nervous system abnormalities, accompanied by multi-organ dysfunction. The severity of cellular and tissue damage in heat stroke patients depends on the peak temperature reached and the duration of hyperthermia. Rapid reduction of core temperature can halt cellular damage, quickly reverse organ dysfunction, and improve patient outcomes. Therefore, early identification and rapid cooling are crucial to prevent irreversible damage and death in heat stroke patients. However, there is a lack of systematic and specific protocols to guide emergency medical staff in the standardized and effective management of body temperature in heat stroke patients. To address this, our research team previously developed an early in-hospital temperature management protocol for heat stroke patients based on the best available evidence, expert consultations, and expert panel meetings. This study aims to validate the feasibility and effectiveness of the protocol through clinical research, providing a basis for clinical practice.
Eligibility
Age Range
Gender
Healthy Volunteers
Detailed Criteria
Inclusion Criteria: * Patients admitted to the emergency department and diagnosed with heat stroke according to the China expert consensus on Heat Stroke Exclusion Criteria: * transferred from another hospital and body temperature \< 39.5℃; discharged within 4 hours, and subsequent body temperature or outcomes were unavailable; required immediate cardiopulmonary resuscitation; had other serious diseases, such as massive cerebral haemorrhage or severe trauma.
Conditions
Interventions
the early in-hospital temperature management protocol for heat stroke patients
The early in-hospital temperature management protocol for heat stroke includes early identification, selection of cooling methods for rapid cooling, precise target temperature management, and dynamic monitoring. Effective temperature management will be implemented for heat stroke patients to improve their outcomes.
OTHERTrial Locations
7 locations currently accepting registrations. Choose a recruiting location below to register your interest.
Yongkang First People's Hospital
Yongkang, Zhejiang, China
Dongyang People's Hospital
Dongyang, China
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hanzhou, China
Jinhua Municipal Central Hospital
Jinhua, China
Jinhua People's Hospital
Jinhua, China
Lanxi People's Hospital
Lanxi, China
Yiwu Central Hospital
Yiwu, China
Sponsor Information
Lead Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Type: OTHER